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Example of non sedating antihistamine

Prescription drug use in the first trimester has increased by over 60 percent in the last 30 years.In addition, use of four or more medications in the first trimester tripled.

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The safety of many drugs in pregnancy are not known because pregnant women are excluded from drug research studies due to safety concerns for the unborn baby.No additional bisphosphonate may be approved for 365 days following zoledronic acid infusion. Clinical Exceptions: Most recent Hb levels (and date obtained) should be included on petition. Authorization can be granted for up to 8 weeks following the final dose of myelosuppressive chemotherapy in a chemotherapy regimen.Authorization for surgery patients will be for a maximum of 4 weeks.Dose of levalbuterol requested cannot be less than the racemic equivalent documented on the prior authorization request.PA criteria: Nasal allergy medications will be included in product-based prior authorization effective 4/28/08.Although animal studies can provide some information about drug toxicity in pregnancy, these results cannot be safely extrapolated to humans.

Roughly 10 percent of birth defects result from drug exposure in pregnancy.

According to the FDA, there are about six million pregnancies in the U. each year, and 50% of pregnant women say that they take at least one medicine.

This raises concern as some medications used during organogenesis (the time period of organ development in the first 12 weeks) can be associated with developmental abnormalities.

For women with chronic conditions such as asthma, epilepsy or heart conditions, medication may need to be continued throughout pregnancy.

And it's important to remember that in every pregnancy there is a 3-5% chance of having a baby with a birth defect, even if you take no medications.

In the past, FDA had established prescription drug pregnancy risk categories as A, B, C, D or X.